10 Best Healthcare AI Companies in the US | 2025 Updated List

Healthcare AI companies are on the rise because they are able to solve complex medical problems by using technology.

The healthcare industry is undergoing a transformative shift, driven by the rapid adoption of artificial intelligence. Today, healthcare AI companies are not only optimizing operational workflows but also revolutionizing how patient care is delivered.

From automating administrative tasks to developing advanced diagnostic tools, these innovators are using generative AI to enhance efficiency, reduce costs, and save lives.

Generative AI—capable of producing new data, images, or insights based on existing information—is being harnessed to interpret medical images, create personalized treatment plans, and accelerate drug discovery.

In addition to generative AI, other forms like predictive analytics, natural language processing, and machine learning are playing vital roles across healthcare settings.

In this article, we highlight the top 10 healthcare AI companies in the US that are setting new benchmarks in the field. These companies are using cutting-edge technology to improve patient outcomes, support medical professionals, and shape the future of medicine.

Use cases for AI in healthcare

Here are key use cases for AI in healthcare that are transforming the industry:

1. Medical Imaging and Diagnostics

AI is widely used to analyze X-rays, MRIs, and CT scans with incredible accuracy. Tools like computer vision and deep learning detect anomalies such as tumors, fractures, and cardiovascular issues earlier than traditional methods.

2. Predictive Analytics

By analyzing patient data, AI can predict disease risk and potential complications. For example, AI algorithms help forecast heart attacks or strokes before they occur, enabling early intervention and personalized care.

3. Drug Discovery and Development

AI accelerates the R&D process by simulating drug interactions, identifying potential compounds, and predicting outcomes. This dramatically reduces the time and cost of bringing new drugs to market.

4. Virtual Health Assistants

AI-powered chatbots and virtual nurses provide round-the-clock assistance, triage symptoms, schedule appointments, and answer patient queries—reducing the burden on healthcare staff.

5. Clinical Documentation and Workflow Automation

Natural Language Processing (NLP) tools streamline documentation by transcribing and summarizing physician-patient interactions. This reduces clerical work and allows clinicians to focus more on patient care.

6. Personalized Treatment Plans

AI tailors treatments based on genetic profiles, lifestyle, and health history—particularly useful in cancer care and chronic disease management.

7. Remote Monitoring and Wearables

AI enables real-time monitoring of patient vitals through smart devices, improving chronic disease management and alerting providers to urgent conditions.

Top 10 Healthcare AI Companies in the US

Here are the Top 10 Healthcare AI Companies in the US, known for transforming the healthcare landscape through cutting-edge artificial intelligence:

1. Tempus

Tempus is one of the leading healthcare AI companies revolutionizing precision medicine through the power of artificial intelligence and big data analytics. Specializing in oncology, Tempus leverages AI to process massive volumes of clinical and molecular data to help personalize cancer treatment.

Its AI-driven platform organizes unstructured medical records, pathology reports, and genomic data to deliver actionable insights that empower oncologists to make more informed treatment decisions in real time.

What sets Tempus apart from other healthcare AI companies is its ability to create a “learning loop” within its database—where every patient interaction contributes to a broader knowledge base that enhances decision-making for future cases.

The company offers a suite of tools including genomic sequencing, clinical trial matching, and AI-based diagnostics that assist healthcare providers in determining the most effective and personalized care for patients.

Beyond oncology, Tempus is also expanding into other therapeutic areas such as infectious diseases, cardiology, and mental health. With partnerships across major hospitals, research institutions, and pharmaceutical companies, Tempus is not only enhancing patient outcomes but also accelerating drug development and clinical research.

Its work epitomizes how healthcare AI companies are transforming medicine with speed, accuracy, and personalization at the core of their mission.

visit company

2. Butterfly Network

Butterfly Network, best known for its groundbreaking handheld ultrasound device, Butterfly iQ, is a standout among healthcare AI companies for its mission to democratize medical imaging.

The Butterfly iQ device connects to a smartphone and replaces traditional bulky ultrasound machines with a portable, affordable, and easy-to-use solution. What makes this innovation even more powerful is the integration of artificial intelligence to assist in interpreting scans.

The company’s AI software helps users—whether experienced clinicians or practitioners in remote, underserved regions—capture quality images and receive real-time guidance during examinations.

This dramatically reduces the learning curve associated with ultrasound imaging and increases diagnostic accuracy even in low-resource settings. The device is particularly impactful in rural clinics, ambulatory care, and developing nations where access to imaging technology is limited.

Butterfly Network’s approach positions it as one of the most accessible and transformative healthcare AI companies in the U.S.

Its technology not only brings critical diagnostics to patients at the point of care but also reduces delays, unnecessary referrals, and healthcare costs. By combining AI with portability and affordability, Butterfly is leading the charge in making quality healthcare truly global and inclusive.

visit company

3. PathAI

PathAI is a leading innovator among healthcare AI companies, specializing in the use of artificial intelligence to revolutionize pathology. The company’s core mission is to improve patient outcomes by increasing the speed, accuracy, and consistency of disease diagnosis through AI-powered pathology slide analysis.

By leveraging deep learning algorithms, PathAI’s platform can quickly and precisely identify disease patterns, helping pathologists detect cancers and other conditions more efficiently than traditional methods.

One of the major strengths of PathAI’s technology lies in its ability to reduce human error and variability in diagnoses, which is especially crucial in fields like oncology where treatment decisions hinge on accurate readings. In addition to diagnostics, the company plays a key role in pharmaceutical research, partnering with drug developers to enhance biomarker discovery, stratify patient populations, and optimize clinical trials.

PathAI’s tools are designed to integrate seamlessly into existing lab workflows, making adoption easier for hospitals and research institutions. With a focus on both healthcare and life sciences, PathAI is not only transforming how diseases are diagnosed but also accelerating the development of new therapies.

Its AI-powered solutions represent a significant leap forward in the pursuit of precision medicine, firmly establishing it among the most impactful healthcare AI companies in the U.S.

visit company

4. Caption Health

Caption Health stands out among healthcare AI companies for its pioneering work in AI-guided ultrasound technology. The company’s platform empowers healthcare providers—even those without specialized training—to capture diagnostic-quality ultrasound images using real-time, on-screen guidance powered by artificial intelligence. This capability is transformative, particularly in settings where access to skilled sonographers is limited.

The software uses deep learning to interpret ultrasound probe positioning and provides instant feedback, ensuring that high-quality images are obtained consistently. This real-time assistance helps clinicians diagnose conditions earlier and more accurately, which can significantly impact patient outcomes—especially in cardiac care, where early detection of heart disease is critical.

Caption Health’s AI platform is FDA-cleared and has been integrated into handheld ultrasound devices, making it highly portable and ideal for use in urgent care, primary care, and remote or underserved communities. It democratizes access to essential diagnostic imaging, reducing the barriers to timely and effective care.

By bridging the gap between advanced imaging and clinical accessibility, Caption Health exemplifies how healthcare AI companies can extend the reach of life-saving technology. Their innovation is helping shift diagnostic capabilities closer to the patient, ultimately leading to more equitable and efficient healthcare delivery.

visit company

5. Freenome

Freenome is a leading innovator among healthcare AI companies, leveraging advanced machine learning and multi-omics technology to enable early detection of cancer through a simple blood test. Their approach centers around analyzing cell-free biomarkers in the bloodstream—signals that cancers may be developing even before clinical symptoms arise.

The company’s AI platform integrates genomic, epigenomic, transcriptomic, and proteomic data to build predictive models capable of identifying the earliest molecular traces of cancer. By doing so, Freenome aims to shift cancer diagnosis from late-stage to early-stage, where treatment options are more effective and survival rates significantly improve.

Freenome’s flagship initiative focuses on detecting colorectal cancer, but their platform has the potential to expand to multiple cancer types. The ongoing clinical trials, including the PREEMPT CRC study, highlight their commitment to evidence-based innovation and regulatory rigor.

What sets Freenome apart from other healthcare AI companies is its holistic view of the body’s immune and biological response to cancer. Instead of looking only for tumor DNA, their AI models analyze how the entire body reacts to cancer, providing a broader and potentially more accurate detection method.

Freenome’s fusion of machine learning, genomics, and clinical insight represents a promising future where early cancer detection becomes routine, accessible, and lifesaving.

visit company

6. Olive

Olive is a standout in the realm of healthcare AI companies, known for transforming healthcare operations through intelligent automation. Unlike companies focused solely on diagnostics or patient-facing tools, Olive addresses a critical but often overlooked area—administrative workflows.

By automating time-consuming processes like prior authorizations, medical billing, claims management, and patient eligibility checks, Olive helps healthcare organizations run more efficiently and reduce operational overhead.

At the heart of Olive’s platform is an AI-powered digital workforce that integrates with existing healthcare systems, such as EHRs (Electronic Health Records) and revenue cycle management software. This automation doesn’t just eliminate repetitive manual tasks—it also minimizes human error, accelerates approvals, and improves overall financial performance.

Hospitals and health systems using Olive report increased productivity, lower administrative costs, and faster turnaround times for patient services. Olive’s real-time data insights also support better decision-making across departments.

What sets Olive apart from other healthcare AI companies is its focus on the business side of healthcare. It enables institutions to spend less time on paperwork and more time on patient care.

By bridging gaps between disparate systems and automating routine tasks, Olive plays a crucial role in modernizing the healthcare infrastructure—making it more responsive, efficient, and financially sustainable.

visit company

7. Viz.ai

Viz.ai is a leading innovator among healthcare AI companies, widely recognized for its groundbreaking work in stroke detection and emergency care coordination. The company’s flagship product leverages artificial intelligence to analyze CT scans in real time and detect suspected large vessel occlusions (LVOs)—a severe type of stroke.

When such a case is identified, Viz.ai’s platform immediately notifies the relevant medical professionals, ensuring that the right specialists are alerted without delay.

This rapid-response system dramatically reduces the time between imaging and treatment—often referred to as “door-to-needle” time—which is critical in stroke care where every minute counts. Studies show that faster intervention can significantly improve patient outcomes and reduce the risk of long-term disability.

Beyond stroke detection, Viz.ai’s platform facilitates seamless communication among neurologists, radiologists, and surgeons through secure messaging and image-sharing tools, promoting faster and more coordinated care.

What sets Viz.ai apart from other healthcare AI companies is its FDA-cleared solution that’s already in use across hundreds of hospitals in the United States. By harnessing real-time data and automating diagnostic alerts, Viz.ai is revolutionizing emergency medicine and showcasing the life-saving potential of AI in healthcare.

visit company

8. Zebra Medical Vision

Zebra Medical Vision stands out among healthcare AI companies for its advanced use of AI algorithms in medical imaging analysis.

The company’s technology is designed to detect a broad spectrum of diseases—from cardiovascular conditions to cancers—by interpreting imaging data with high accuracy and speed.

Zebra’s AI-powered platform integrates seamlessly into radiology workflows, providing automated insights that support early diagnosis and improve clinical decision-making.

Used globally across hospitals and imaging centers, Zebra’s solutions help radiologists identify abnormalities faster and reduce the risk of missed diagnoses. Their scalable AI tools enhance diagnostic precision while optimizing efficiency, making advanced imaging analysis accessible even in resource-constrained settings.

What distinguishes Zebra from other healthcare AI companies is its commitment to delivering clinically validated algorithms that address multiple pathologies, providing a comprehensive approach to imaging diagnostics.

This innovation not only improves patient outcomes through timely detection but also eases the workload on healthcare professionals, empowering radiologists to focus on complex cases and personalized care.

visit company

9. Eko

Eko is a leading name among healthcare AI companies, merging artificial intelligence with cutting-edge digital stethoscope technology to transform cardiac care.

Their AI-powered devices are designed to detect heart murmurs and arrhythmias with remarkable accuracy, offering early diagnostic support right at the point of care.

Eko’s AI algorithms have received FDA clearance, underscoring their reliability and clinical relevance. By equipping primary care providers with advanced tools, Eko enables faster identification of cardiovascular issues, facilitating timely referrals and improved patient outcomes.

This technology is especially valuable in busy clinics and underserved areas where access to specialists may be limited.

What sets Eko apart from other healthcare AI companies is its seamless integration of hardware and AI software, delivering real-time, actionable insights during routine examinations.

Their commitment to enhancing early detection while simplifying clinical workflows makes them a vital player in modern cardiac diagnostics, improving care quality and efficiency across diverse healthcare settings.

visit company

10. Arterys

Arterys stands out among healthcare AI companies by delivering advanced cloud-based medical imaging solutions powered by artificial intelligence.

Specializing in radiology and cardiology, Arterys’ platform significantly improves diagnostic speed and accuracy, helping clinicians make more informed decisions in complex cases such as oncology and heart disease.

Their cloud infrastructure enables real-time image processing and collaboration across medical teams, removing traditional barriers of on-site hardware limitations. This accessibility allows healthcare providers to analyze large volumes of imaging data quickly, accelerating diagnosis and treatment planning.

What makes Arterys a leader in the field of healthcare AI companies is its focus on integrating AI seamlessly into existing workflows while maintaining high clinical standards.

By enhancing the precision of imaging interpretations and providing scalable, secure cloud solutions, Arterys empowers hospitals and clinics to deliver better patient outcomes in some of the most critical areas of medicine.

visit company

FAQs

What are healthcare AI companies?
Healthcare AI companies develop artificial intelligence technologies to improve medical diagnostics, patient care, administrative tasks, and treatment planning in the healthcare sector.

How does AI improve healthcare diagnostics?
AI analyzes large datasets and medical images faster and more accurately than traditional methods, helping detect diseases early and supporting clinical decisions.

Are AI tools from healthcare companies safe and reliable?
Yes, many healthcare AI solutions undergo rigorous testing and regulatory approval, such as FDA clearance, to ensure safety and effectiveness.

Can AI healthcare companies assist with administrative tasks?
Absolutely. AI automates repetitive tasks like billing, scheduling, and prior authorizations, reducing costs and freeing up staff for patient care.

Will AI replace doctors and healthcare professionals?
No, AI is designed to assist—not replace—medical professionals by providing decision support and improving efficiency, allowing doctors to focus more on patient care.

Conclusion

Healthcare AI companies are transforming the medical field by enhancing diagnostics, streamlining operations, and personalizing patient care.

Their innovative solutions improve accuracy, efficiency, and outcomes, making AI an essential partner in modern healthcare. Embracing these technologies is key to advancing the future of medicine and patient well-being.

10 Best Healthcare AI Companies in the US | 2025 Updated List